Death is nothing new to Supernatural. But this time, the Grim Reaper will be claiming 2 more souls who may be fan favorites, according to Michael Ausiello:
Question: How about a Supernatural spoiler? —Kriya
Ausiello: The Grim Reaper will set his sights on two recurring characters in the not-too-distant future.
I'm hearing one of the dearly departed will be Rufus. Who do you think Death is coming for?