Check out the episode guide for the 7th episode of Season 7, “A Pox on Our House,” airing November 15 on Fox.
- After a 200-year-old medicine jar found on an off-shore shipwreck shatters in a teenage girl's palm, she is admitted to Princeton Plainsboro for symptoms closely linked to smallpox.
- When the Center for Disease Control's Dr. Dave Broda (guest star Dylan Baker) institutes a lockdown on the hospital and suspends House's team's ability to diagnose, Masters (guest star Tamblyn) grows suspicious of Broda's motives and becomes convinced that the patient is suffering from a different disease.
- The girl's father soon experiences similar symptoms, and House is forced to make a precarious decision that puts his own life in jeopardy.
- Meanwhile, Wilson (Robert Sean Leonard) and Sam (guest star Cynthia Watros) comfort a 6-year-old chemotherapy patient (guest star Devon Woods) who prompts them to examine their relationship.