General Grey's Anatomy spoilers are great but spoilers on ALL the Grey's Anatomy couples is even better.. so go on, check them out!
Mer-Der: These two will keep dealing with infertility issues which will become more obvious during next week's musical episode. As for their Alzheimer's clinical trial, it will "launch into a very big story about them as we head towards the end of the season." But about this "big story", it will be good news for Grey's Anatomy's golden couple!
Cristina-Owen: While Mer's trying to get pregnant, Cristina's on the opposite end. It's almost as if Cristina and Owen didn't cover all the fundamental things before getting married and this will be something that'll cause problems for them, especially as this season unfolds. Bad news, Cristina-Owen fans.. showrunner Rhimes says that, "I don't think the end of the season is going to be easy for any of our fans, but I think it's going to be pretty explosive for [the Cristina-Owen ones]."
Calzona: Although Rhimes thinks that these two are "MFEO: made for each other," the issues between these two will also come to a head during the musical episode.
Mark-Lexie-Jackson triangle: No actual spoilers on this triangle but Chyler Leigh, the actress who plays Lexie, thinks that Jackson's not just a rebound for her character.. there may be something there. Leigh points out that the two are in the same place and that "it's definitely something that has the potential to blossom into something pretty big."
April and Stark: As we saw in last night's episode, these two had a little bit of a miscommunication. As for April's virginity, tis still intact. Sarah Drew, the actress who plays April, says that "She's not losing her virginity for awhile. The [writers] promised me that it will be beautiful."
Alex and Lucy: Isn't it great that Alex is finally getting a love interest? Anyway, these two will share a smooch before Rachael Taylor, the actress who plays Dr. Lucy, exits to join the cast of Charlie's Angels.
Bailey and Eli: Expect these two to sing with the other couples on next week's musical episode. Chandra Wilson, the actress who plays Bailey, thinks that Bailey isn't really at the place where she would call her trysts with Eli a "relationship."
Source: TV Guide