Grey's Anatomy Season 10 Spoilers: Everything You Need To Know

Grey's Anatomy Season 10 Spoilers: Everything You Need To Know

With only days away from the monumental tenth season premiere of Grey's Anatomy, you must be starving to know what's on deck for the surgeons of Grey Sloan Memorial. As you may recall, the ninth season cliffhanger had put series lead Meredith (Ellen Pompeo) and Webber's (Richard Pickens Jr.) life in jeopardy.

What state are they in when season 10 returns? Has the storm passed?

To answer your burning Q's, we've rounded-up everything we've learned about the Shonda Rhimes drama in the previous months.

Keep reading for the spoilers:


1. Seattle firefighters, the aftermath of Mer's pregnancy and a mudslide.

The 2-hour premiere titled "Seal Our Fate", is going to be a rough couple of days for the doctors in Grey-Sloan Memorial as the series picks up where we left off last May, meaning no time-jump.

"We’re continuing on where we left off last season. It’s continuous and it feels like it, too. The storm is continuing on and we pick up right where we left off. We’re still dealing with the crisis of what’s happening with the storm,"  Patrick Dempsey previewed.

As learned via casting scoop, the season 10 opener will feature a major accident involving a group of Seattle fire fighters. But that's not the only major case the doctors are gonna have to deal with. As a result of the superstorm in the finale, expect for Dr. Owen Hunt and co. to get their hands full with the casualties of a mudslide.

On the same hour, prepare to meet two new characters: (pictured above) Brian, a fireman and Sasha, a tough cop. They are an engaged couple who are both involved in the said accident. They will be played by Being Human alum Bobby Campo and Hellcats actress Heather Hemmens.

Meanwhile, with all the chaos happening on the ER, the premiere will also scope around Meredith's recovery after her traumatic delivery. "She had a rough birth. We’re going to see them in the hospital together and juggling their roles in a major way,” teases consulting producer Dan Bucatinsky.

greys-anatomy-200-episode-celebration 2. A remarkable 200th Episode

Though not much information is known about Grey's 200th episode milestone (happening in ep.4), we hear that it was a blast.  Series regular Patrick Dempsey has shared how the cast reveled the special moments on his chat with THR, "Everybody was really celebrating the achievement. There was openness and a joy in the entire room. It was a remarkable day."


3. Dr. Shepherd on Obama's brain mapping
Dr. Shepherd's season 10 trajectory is learned to be Pres. Obama's proposal on 'brain mapping'. Per Huffington Post, the president's latest medical agenda in D.C. is "an effort to map the brain's activity in unprecedented detail, as a step toward finding better ways to treat such conditions as Alzheimer's, autism, stroke and traumatic brain injuries."

Dempsey has echoed his thoughts on the same subject on a recent interview. "I think it will be fun for Shepard to get into that, it’s a fascinating thing. I’ve been starting to look at the research on that and what they’re trying to achieve. I’m excited about that storyline. The writers are really getting into it. I think it would be fun to see Shepard go to D.C. and be part of the brain mapping," the actor said.

4. An angry but funny season for Callie and Arizona

Series creator Shonda Rhimes has warned that a reconciliation for Calzona is probably not in the cards. However, she explains that they aim to tell the story with a little humor, rather than on a miserable tone.

“I want this season to feel lighter and funnier for everybody, and even in Callie’s pain, it’s very funny,” Rhimes promises. “Its painful in a funny way as opposed to just dragging us down in misery.”

On that note, Sara Ramirez, the portrayer of Callie has previewed some funny scenes we can look forward to around the Calzona orbit. On her chat with TV Line she shares, “We’re going to see in the first few episodes Callie being reactive and acting out, dealing with her own feelings about what’s happening. Callie doesn’t hide it from the hospital, how she’s feeling. No, she lets it be known!”


5. Cristina Yang is leaving at the end of season 10

One of this year's shocker on TV is Sandra Oh's nearing exit on the medical juggernaut after a decade. Obviously, fans weren't delighted of the news as many of the favorites have already been dead and gone. (We miss you Slexie)

Now that the big news is out, Shonda has weighed in and shares that Cristina will get “the exit she deserves.”

6. Owen and Cristina are on 'splitsville'

Even though many fans are rooting for Owen and Cristina, some things are just really not meant to happen. Especially now that we learned of Sandra Oh's exit, we can only hope so much for Owen's happiness.


When season 10 opens, expect for the broken up couple to remain on splitsville and maybe even stay their longer. As explained by Kevin Mckidd, "The problem they have is they really kind of are the loves of each other’s lives, but they have fundamental, opposing, strong beliefs. So is one of them going to back down? I don’t know.”

When asked about if Owen may find happiness even without Cristina in his life, the actor/director thinks that Owen hasn't lose hope. "I want him to pursue it to see what happens, but the sad fact is that if he gets what he wants, he’ll lose the person he loves, so it’s a real catch-22," Mckidd told TV Line.

7. A challenging season for Jackson and April; Jo and Alex headed to 'Happy Camp'.

For Jolex fans, season 10 is a good news. For Japril, not so much.


April Kepner got engaged with EMT Matthew in season 9. Avery, on the other hand, has been busy doing non-surgical things with intern Stephanie. When Jackson appeared out of the fog alive in the finale, April flipped out. She kind of had an epiphany that she almost lost the person she actually loves. Moments later, we see her furious and giving Jackson a declaration-of-love speech.

As a basketcase that she is, Kepner will face the consequences of her feelings and actions on the premiere. As previewed by Rhimes, "He’s been very patient, and she’s the one who sort of walked away from him. And when the finale happened, he was feeling kind of ‘done,’ so her declaration is definitely going to have interesting repercussions. She’s engaged to somebody else, and he’s with somebody else, and it’s not as if either of them is behaving, I would say, in the most mature manner. They’ve definitely got challenging times ahead.”

Jo and Alex:joalex

The dark storyline of Jo and Alex that involves the subject of physical abuse has been finally put to rest. And though Alex tried very hard to veer away from highly-convoluted women, Shonda Rhimes just kept on pushing.

After some conflicts thrown into their relationship in season 9, as expected, Jo and Alex will eventually hit it off. As teased by Camilla Luddington, the duo is "crazy about each other and in love". When we see them in season 10, expect for a fun ride. "I want us to have fun with them” as they explore their new romance. Because they’re one of our happiest couples, Jo and Alex are playing our humor a lot, which is nice,” Rhimes has enthused. 


8. Webber the survivor 

The last time we saw Richard Webber, he was lying on the floor unconscious after electrocuting himself during the storm. Though no spoiler reports have arise involving Webber's status, the Twitter account of Shonda Rhimes has been helpful in extracting credible scoops.

In one photo 'accidentally' posted by the showrunner, actor Richard Pickens Jr. is seen with his co-actors while on the set. A few moments later, the photo was deleted with a regretful follow-up that says, "Crap". The incident has stirred up speculations that though unofficially confirmed, the former Chief of Surgery of Seattle Grace has survived his near death experience. Thus ensuring his tenure in season 10.


9. Upcoming guest stars

In addition to the aforementioned Bobby Campo and Heather Hemmens, two more guest stars have been reported to appear on the medical drama's tenth season.

We learned earlier that Dexter actor James Remar will play a mysterious character. A recent scoop confirms that he will first air early into the upcoming season.

Another notable guest star to join Grey's is the X-Files actress Veronica Cartwright. Details are also kept under wraps on her character but we know that she is also slated to appear on the two-part premiere.

Season 10 of Grey's Anatomy airs on Thursday, Sept. 26 at 9pm on ABC.