- Ben worries that a casual conversation with Derek could potentially cause issues for Bailey.
- Cristina turns to Shane as tension grows with Meredith.
- April's upcoming wedding makes for an uncomfortable situation between Jackson and Stephanie.
- Meanwhile, Meredith plans a Thanksgiving dinner at her house.
"Grey's Anatomy" stars Ellen Pompeo as Meredith Grey, Patrick Dempsey as Derek Shepherd, Sandra Oh as Cristina Yang, Justin Chambers as Alex Karev, Chandra Wilson as Miranda Bailey, James Pickens, Jr. as Richard Webber, Sara Ramirez as Callie Torres, Kevin McKidd as Owen Hunt, Jessica Capshaw as Arizona Robbins, Jesse Williams as Jackson Avery, Sarah Drew as April Kepner, Camilla Luddington as Jo Wilson, Gaius Charles as Shane Ross, Jerrika Hinton as Stephanie Edwards and Tessa Ferrer as Leah Murphy.
Guest cast TBA.
"Somebody That I Used To Know" was written by Deborah Cahn and directed by Debbie Allen.