A spoiler from Ausiello tells us something about how one of the original five interns grew up... check it out and try to guess which of the original five you think it could be!
Question: I want some juicy Grey’s Anatomy news, not somewhat juicy, but very juicy. C’mon you can do it! —Sarah
Ausiello: We’ll find out in an upcoming episode that a major character — one of the original Fab Five — grew up in foster care.
Source: Ausiello Files