• Season 4 Episode 4
  • The Heart of the Matter

  • Airdate:18.10.2007.

The Chief's wife, Adele, rushes their niece to Seattle Grace, the hospital where she once had her prom, Izzie reveals her feelings for George to a mutual friend, and the reaction is not what she expects, Derek teaches Cristina how to be a better teaching resident, and the world's oldest living intern, Norman, misdiagnoses one of Meredith's patients,

series regulars:

    Ellen Pompeo as Meredith Grey
    Patrick Dempsey as Derek Shepherd
    Sandra Oh as Cristina Yang
    Katherine Heigl as Isobel "Izzie" Stevens
    Justin Chambers as Alex Karev
    T.R. Knight as George O'Malley
    Chandra Wilson as Miranda Bailey
    James Pickens, Jr. as Richard Webber
    Sara Ramirez as Callie Torres
    Eric Dane as Mark Sloan
    Chyler Leigh as Lexie Grey.

guest cast:

    Edward Herrmann as Norman
    Michael McGrady as Stanley
    Matt Lanter as Adam
    Maggie Siff as Ruthie
    Miriam Flynn as Ms. Bitzer
    Camille Winbush as Camille
    Ron Melendez as Will
    Loretta Devine as Adele.

written by:

Allan Heinberg

directed by:

Randy Zisk