• Season 4 Episode 15
  • Losing My Mind

  • Airdate:10.05.2008.

Dr. Wyatt refuses to let Meredith give up on therapy, Alex learns the truth about Rebecca's medical condition, the Chief insists that Erica perform a risky surgery on his mentor, and after receiving news of Burke, Cristina continues to do things contrary to her nature, going so far as cleaning her always-messy apartment 

series regulars:

    Ellen Pompeo as Meredith Grey
    Patrick Dempsey as Derek Shepherd
    Sandra Oh as Cristina Yang
    Katherine Heigl as Isobel "Izzie" Stevens
    Justin Chambers as Alex Karev
    T.R. Knight as George O'Malley
    Chandra Wilson as Miranda Bailey
    James Pickens, Jr. as Richard Webber
    Sara Ramirez as Callie Torres
    Eric Dane as Mark Sloan
    Chyler Leigh as Lexie Grey
    Brooke Smith as Erica Hahn

guest cast:

    Amy Madigan

written by:

Debora Cahn

directed by:

Jim Frawley