• Season 3 Episode 20
  • Time After Time

  • Airdate:19.04.2007.

Izzie faces her past and finds comfort in George, while Alex becomes more attached to Jane Doe (Elizabeth Reaser), Meredith and Derek question their own status, and Cristina resolves to fight for her relationship with Burke -- despite her past with Colin Marlow.

series regulars:

    Ellen Pompeo as Meredith Grey
    Patrick Dempsey as Derek Shepherd
    Sandra Oh as Cristina Yang
    Isaiah Washington as Preston Burke
    Katherine Heigl as Isobel "Izzie" Stevens
    Justin Chambers as Alex Karev
    T.R. Knight as George O'Malley
    Chandra Wilson as Miranda Bailey
    James Pickens, Jr. as Richard Webber
    Kate Walsh as Addison Shepherd
    Sara Ramirez as Callie Torres
    Eric Dane as Mark Sloan

guest cast:

    Elizabeth Reaser as Jane Doe
    Roger Rees as Dr. Colin Marlowe
    Dee Wallace as Joan Waring
    Brent Jennings as Charles
    Suzanne Cryer as Caroline Klein
    Tim Hopper as Dustin Klein
    Marc Vann as hematologist
    Steven W. Bailey as Joe
    Mare Winningham as Susan Grey

written by:

Stacy McKee

directed by:

Christopher Misiano