- Season 2 Episode 19
What Have I Done to Deserve This?
Meredith and George suddenly find themselves at odds at work. Meanwhile Bailey, although technically still on maternity leave, finds herself treating Addison for an unusual feminine issue, and Alex finds himself oddly jealous when Izzie pays more attention to Denny.
Ellen Pompeo as Meredith Grey
Patrick Dempsey as Derek Shepherd
Sandra Oh as Cristina Yang
Isaiah Washington as Preston Burke
Katherine Heigl as Isobel "Izzie" Stevens
Justin Chambers as Alex Karev
T.R. Knight as George O'Malley
Chandra Wilson as Miranda Bailey
James Pickens, Jr. as Richard Webber
Kate Walsh as Addison Shepherd