• Season 1 Episode 7
  • The Self-Destruct Button

  • Airdate:08.05.2005.

Derek and Meredith try (unsuccessfully) to be discreet as they spend the night together at Meredith's house, but their haggard appearance speaks volumes to everyone - including Bailey, who warns Meredith to end the relationship. Meanwhile George suspects an anesthesiologist of drinking on the job but is reluctant to speak up about it, Alex treats a former schoolmate who finds honor in self-mutilation, Izzie's boyfriend takes extreme measures in order for them to spend more time together, and Cristina seems to be battling a case of the flu, 


series regulars:

    Ellen Pompeo as Meredith Grey
    Patrick Dempsey as Derek Shepherd
    Sandra Oh as Cristina Yang
    Isaiah Washington as Preston Burke
    Katherine Heigl as Isobel "Izzie" Stevens
    Justin Chambers as Alex Karev
    T.R. Knight as George O'Malley
    Chandra Wilson as Miranda Bailey
    James Pickens, Jr. as Richard Webber.

guest cast:

    Ever Carradine as Athena
    Amanda Macdonald as Claire Rice
    Kim Morgan Greene as Mrs. Rice
    Russell Hornsby as Digby Owens.

written by:

Kip Koenig

directed by:

Darnell Martin