Since Gossip Girl's season 4 won't be starting up until the fall, I'm sure you guys are going through GG withdrawal. Well here are some spoilers from Ausiello on the drama we can expect for next season!
Question: Please tell me that Gossip Girl is not going to play the amnesia card with Chuck next season. —Simone
Ausiello: Gossip Girl is not going to play the amnesia card with Chuck next season. But the little Bass-tard will emerge from his near-death experience a very changed man.
Question: Any Gossip Girl scoop regarding Nate and Serena? Are they really finished? —Kayla
Ausiello: The fact that producers are casting a new love interest for Nate should answer your question.
Source: Ausiello Files